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Arthur J. Olson/Professor in the Department of Molecular Biology at the Scripps Research Institute %93Novel Computational Approaches to Biomolecular Interaction %96 from Viral Drug Resistance to Tangible Molecular Interfaces%94 in ACES 3.408 at 9:30 am

Contact Name: 
Jenna Whitney
Date: 
Dec 5, 2006 9:30am - 10:30am

Olson Talk %96 U. Texas December 2006

Titl

e:

%93Novel Computational Approaches to Biomolecular Interaction %96
from Viral Drug Resistance to Tangible Molecular Interfaces%94

Abst

ract:

Computational technology has had an enormous impact on the stu

dy of biomolecular structure and interactions. This talk will describe two
areas of current interest in my laboratory: Very large scale molecular do

cking studies and human computer interfaces for research and education.
First I will discuss computational molecular docking and its use in t

he design of HIV inhibitors in the face of evolving drug resistance. A com

putational co-evolution approach and its implementation on an Internet dist

ributed computing platform will be described. Secondly I will describe and
demonstrate the application of two emerging computer technologies autofab

rication and augmented reality in the creation of a novel interface for exp

loring and computing with physical molecular models.

Brief Bio
Arthur J. Olson is a Professor in the Department of Molecular Biology
at the Scripps Research Institute where he holds the Anderson Research Cha

ir. He is the founder and Director of the Molecular Graphics Laboratory at

the Institute.
He came to TSRI in 1981 to help establish a structural m

olecular biology program at the Institute. His group works at the interfac

e between chemistry biology and computer science to develop and use comput

er modeling to help predict and understand the nature of molecular interact

ions in living systems. Software developed in his laboratory is used to vi

sualize proteins and nucleic acids and to help design new drugs and other b

ioactive molecules and is used worldwide.