Interaction with Expert

Test cases often reveal missing pieces of knowledge.

Example: Fever of Unknown Origin

Patient is 17-year-old female; persistent fever, headache, lethargy, cardiac symptoms, ...

Diagnoses: Lung cancer (.81), Endocarditis (7).

Correct diagnosis was endocarditis. Physician expert said the diagnosis of lung cancer was consistent with the symptoms; however, lung cancer would never be expected in a patient this young.

Result: new rules added to rule out certain cancers in young patients. Patient age can be used to determine certainty factor of ruling out lung cancer.

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