ICES/TACC Seminar: Dr. Gordon Kindlmann Brigham and Women's Hospital *%93Anisotropy Creases and Geodesic-Loxodromes: * *Recent Developments in the Analysis and Interpolation of Diffusion Tensor Images%94 ACES 6.304 Tuesday August 2 2007 3:30 p.m.

Contact Name: 
Jenna Whitney
Date: 
Aug 2, 2007 3:30pm - 5:00pm

Type of Talk: *ICES/TACC SEMINAR*

Speaker/

Affiliation: *Dr. Gordon Kindlmann Department of Radiology Brigham and W

omen''s Hospital Harvard Medical School

Date/Time: Tuesday August
2 2007 3:30 p.m.

Location: ACES 2.402

Host: Dr. Chandra

Bajaj ICES and Dr. Kelly Gaither TACC

Talk Title: %93Anisotropy C

reases and Geodesic-Loxodromes: Recent Developments in the Analysis and Int

erpolation of Diffusion Tensor
Images%94

Talk Abstract:

D

iffusion Tensor MRI (DTI) has become a popular way of
non-invasively as

sessing micro-structural orientation and
organization in biological tis

sue especially the central nervous
system. In algorithms for processin

g DTI a common ingredients
is interpolating between two tensor values.
We describe a new
class of interpolation paths for tensors termed geo

desic-loxodromes
which explicitly preserve clinically important tensor
attributes such
as mean diffusivity or fractional anisotropy while u

sing basic
differential geometry to interpolate tensor orientations. On
the
other hand simpler tensor interpolation methods can indirectly reveal features in fiber tract orientation through the differential
s

tructure of field. We describe a method of extracting surface
models fr

om DTI called anisotropy creases which is based on
traditional method

s of ridge and valley feature extraction applied
to the (non-linear) a

nisotropy field computed from a
second-order-continuous tensor field. R

esults from anisotropy
creases suggest that they may be used to form a

skeleton for the
major white matter features in the brain.