Chandrajit Bajaj
Left image shows an Iso-surface Rendering of the Haloarcula Marismortui Large Ribosomal 50S subunit (1JJ2) crystal structure(cf. Klein, Schmeing, Moore, Steitz) and based on protein and RNA classification. Light Yellow and Pale Pink are the 5S and 23S Rrna while the remaining colors are proteins.

Additional images and movie for models of ribosomal structures


Research Interests


Computational Biology, Image Processing, Computational Geometry, Geometric Modeling and Optimization, Computer Graphics, Compression, Mesh Generation, Scientific Computation, and Visualization

 

My research interests span the algorithmic and mathematics underpinnings of Structural Biology and Biophysics, Image Processing, Geometric Modeling, Computer Graphics, and Visualization. Current research initiatives include (a) structure elucidation and reconstruction of spatially realistic models of molecules(drug targets), organelles, cells, tissues, and organs, from electron microscopy, and bio-imaging,, (b) fast high-dimensional search engine for identifying energetically favorable molecular binding conformations (e.g virtual screening for anti-viral drugs), and (c) integrated approaches to computational modeling, mathematical analysis and interrogative visualization, in particular, of the dynamics of electrical signaling and oscillations (3-10 Hz) amongst neurons in the hippocampus (the central area of learning and memory).

 

My research is currently sponsored by grants from the National Science Foundation (NSF) and the National Institutes of Health (NIH).

 
My research publications are available here, as is my Curriculum Vitae. Click here for Google Scholar Citations